well with a 6:1 reduction gearbox,
you can get a very low ratio for the final drive (clutch out-> axle)
Say 1:1 if it'd been a 100lbs street kart with 10-11" wheels
Start with twenty teeth each.
add one tooth to your axle sprocket for every 50lbs more, every 2" of added wheel diameter and every 10° road inclination you intend to climb
so a 200lbs kart with 18" wheels going 20° up hill
end up having 20 on the clutch and 28 on the axle
that'd be 1.4:1 final ratio times 6:1 clutch ratio or 8.4:1 overall ratio
sounds about right to me

(
WARNING: this is an estimation!! Not a proven formula)
'sid