I've been running Methanol in my 4-stroke race kart engine for a couple years. To gain the benefits of using this fuel my engine has extra high compression and more advanced timing. All this ends up producing somewhere around 25% more power than I could with Gasoline, but running this fuel does come with some drawbacks:
Methanol powered engines typically end up consuming about twice as much fuel as equivalent gasoline engines, so your jetting would need to be much richer. This very rich mixture tends to wash down past the rings and ends up polluting/breaking down your engine oil.
Methanol also tends to absorb moisture from the air, this ends up corroding the carb and my fuel pump unless its all flushed out. Methanol also tends to soften plastic and some rubber fuel lines/components.
So after each day of racing I go through the extra hassle of completely draining my fuel tank, and then run the engine on gasoline for a short time to flush all the Methanol out. After that I Immediately change the oil so any moisture or dirt will still be suspended in the oil.
Another drawback is pure Methanol doesn't offer any Top-end lubrication like Gas does, so I mix in an additive sold by VP Fuels. (although some racers buy the more expensive Methanol grade with additives, or just pour in a little 2-stroke premix oil instead)
You could experiment with adding a little of your home brew to gas, but I doubt you'd notice much difference unless you had more compression/timing and the correct jetting to reap the benefits of running pure Alcohol.