Hmm, your life just became a whole lot more difficult...
I'm assuming the stock kart didn't have multiple gears so, no shifter or clutch mechanisms, these will need to be added (not difficult, just a pita)...
Then you need to figure out the gear ratios so we can suggest the optimal ratio between the engine & the final drive input shaft...
Until you advise otherwise, for now, lets assume the tyres ar 18" & the engine has a max RPM around 7000...
Given those figures & the 6:1 diff ratio, with a 1:1 ratio between the engine & diff, in top gear @ WOT, that thing will do 60+mph & still spin the tyres in first gear...